Nature Made Creatine Powder is an unflavored, micronized creatine monohydrate drink mix, and its maker says it supports muscle strength, muscle function and healthy aging when used with resistance training. Each level scoop is 5 g of creatine monohydrate, and the seller says it is for adults 18 and over. As of October 28, 2026, the seller's product page lists it at $21.99 as a one-time purchase, or $19.79 per shipment with Subscribe & Save, which repeats on a delivery schedule you pick until you change or cancel it. Returns are handled through the seller's help center, so check the return window there before you order. Numerous clinical trials, as summarized by the NIH Office of Dietary Supplements, generally show a benefit for high-intensity, intermittent activity. This page covers what the seller says, the label, the price and subscription terms, the research on creatine, side effects, whether the brand is legit, and how it compares with other creatine options.
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| What it is | Unflavored micronized creatine monohydrate drink mix powder, 5 g per level scoop |
| Who sells it | Nature Made, sold on its own site, naturemade.com. The label says it is distributed by Nature Made Nutritional Products. |
| Price as shown and when | $21.99 one-time purchase; $19.79 per shipment on Subscribe & Save (as of October 28, 2026) |
| Subscription | Choosing Subscribe & Save sets up repeat shipments every 30, 45, 60 or 90 days, at the interval you choose. You can change, pause or cancel before the next shipment date. |
| Returns | Through the seller's help center for orders, shipping, returns and subscriptions |
| Contact the seller | 1-800-276-2878 or www.NatureMade.com. The label lists a mailing address on the back of the package. |
| Product Page | Where to Buy |
What is Nature Made Creatine Powder, and who is it for?
It is a drink mix powder, not a capsule or gummy. The seller's directions say to mix one level scoop into 4 to 6 oz of water or another beverage, preferably at room temperature or warm. The product page says the powder dissolves more easily in room temperature or warm liquid.
The seller says the product is for any adult over 18 who wants to build muscle mass and strength with resistance training. It also says older adults can take one scoop a day to support muscle health and healthy aging. The label says it is not for anyone under 18, so keep it away from younger people in your home.
Age rules are stricter in some places. The product page says some states prohibit sales of products that may be considered for weight loss or muscle building to people under 18. It also says that, due to shipping constraints, someone 21 or older must show ID and sign for delivery in those states. Check your local laws before you buy.
What does the seller say it does, and how is it supposed to work?
Nature Made's maker says the powder supports healthy aging, muscle strength and function, and cellular energy metabolism in muscle. On the product page, these claims carry a note that they apply in combination with resistance training. The package badge says the powder helps support healthy muscle strength, power and recovery.
The seller describes creatine as something that supplies energy to your muscles during physical activity, and it says the supplement is best taken before or after short-term, high-intensity exercise or resistance training. It also says you should not expect an immediate benefit and that consistency is key.
The seller's awards claim is that the product was named Best Creatine Powder by the 2026 Shape Fitness Awards. It also calls Nature Made the #1 Pharmacist Recommended Vitamin and Supplement Brand, based on a survey of pharmacists who recommend branded vitamins and supplements.
For the general mechanism, Cleveland Clinic's creatine page explains that most creatine goes to skeletal muscle, where it helps the body keep a steady supply of ATP, the energy source your cells use during exercise.
What is in each scoop?
| Product name on the page | Micronized Creatine Monohydrate 5 g Drink Mix Powder (Item #HL000822) |
| Form | Unflavored drink mix powder |
| Form of creatine | Creatine monohydrate, micronized |
| Serving size | 1 level scoop (5 g) |
| Creatine per serving | 5 g creatine monohydrate. The label marks the % Daily Value as not established. |
| Servings per container | 40 on the 7.2 oz (200 g) pack. The seller's page offers 40 and 90 count options; check the Servings Per Container line on the package you receive. |
| Other ingredients | Check the panel on your package. |
| Label claims | No artificial colors, no flavors, gluten free, no preservatives, vegetarian |
| Seal | Tamper-evident seal under the cap. The label says not to use the product if the seal is broken or missing. |
| Storage | Store tightly closed in a cool, dry place, out of reach of children |
One thing to check: the seller's page offers 40 and 90 count options. The package images on the page show a 40-day supply (7.2 oz) and a 57-day supply (10.1 oz). At 5 g per scoop, 286 g is about 57 scoops. Check the Servings Per Container line on the package you receive.
What does the research say about creatine?
This section covers creatine in general, not this product. Antonio et al. 2021 (J Int Soc Sports Nutr 2021;18:13) says evidence-based research clearly shows creatine monohydrate to be the optimal choice.
- High-intensity work. The NIH Office of Dietary Supplements says numerous clinical trials generally show a benefit for high-intensity, intermittent activity, and may increase strength, power and work from maximal-effort muscle contractions. It also says creatine is of little value for endurance sports. The NIH fact sheet gives a typical loading dose of 20 g a day for up to 7 days, and 3 to 5 g a day for up to 12 weeks.
- Position stand. The 2017 International Society of Sports Nutrition position stand says creatine supplementation increases intramuscular creatine concentrations, which may help explain improvements in high-intensity exercise performance. It reports that short- and long-term supplementation of up to 30 g a day for 5 years is safe and well tolerated in healthy individuals. That is six times the 5 g scoop on this label, so the dose on the label is the one to compare.
- Loading phase and form. Antonio et al. 2021 says a loading phase is not required, and that creatine monohydrate is the optimal choice. The label directs one scoop a day with no loading phase.
- Who has been studied. Antonio et al. 2021 notes that the evidence for children and adolescents is limited. It also says a growing body of evidence shows musculoskeletal and performance benefits in older adults, particularly when combined with exercise. For women, it describes accumulating evidence with little to no side effects. This product's label says it is not for anyone under 18.
- Muscle gain. Cleveland Clinic says studies show regular creatine use with weight training can help increase muscle growth in people 18 to 30. It also says there is not enough research to say the same for people over 65 or people with diseases that affect their muscles. Some studies show an extra two to four pounds of muscle over four to 12 weeks of regular exercise.
For a plain-language overview of the human studies and safety record, see Creatine Benefits: Human Studies, Side Effects and Safety (our research library).
Several authors of the ISSN's creatine publications report funding from, or advisory roles with, companies that make or sell creatine, including AlzChem, a creatine manufacturer. Read that work with that in mind.
Side effects, safety and who should not use it
The NIH fact sheet says few safety concerns are reported at typical doses. It lists the following adverse effects, and Antonio et al. 2021 adds notes on water retention, kidneys, hair and hormones.
| Effect | What the sources say |
| Weight gain from water retention | NIH lists it as a reported effect. Antonio et al. 2021 says creatine may increase water retention over the short term, but not always, and other studies suggest total body water relative to muscle mass does not change over longer periods. |
| Nausea and diarrhea | NIH lists these as anecdotal reports. |
| Muscle cramps and muscle stiffness | NIH lists these as anecdotal reports. |
| Heat intolerance | NIH lists this as an anecdotal report. |
| Kidneys | Antonio et al. 2021 says that at recommended dosages, creatine does not result in kidney damage or renal dysfunction in healthy individuals. |
| Hair loss and hormones | Antonio et al. 2021 says the current body of evidence does not indicate that creatine increases total testosterone, free testosterone or DHT or causes hair loss or baldness. It says the speculation stems mainly from a single study of college-aged male rugby players. |
If side effects develop, Cleveland Clinic suggests dividing the daily amount into smaller doses taken through the day, and talking to a healthcare provider about any side effects you have.
Who should ask a clinician first. Cleveland Clinic says a provider will likely ask whether you have diabetes, kidney disease or liver disease, and whether you take any medications, vitamins or other supplements. The label says to consult your physician before use if you are planning lab testing, are pregnant or trying to become pregnant, are nursing, take any medications, or have a medical condition. The product page also advises consulting a healthcare professional if you take prescription medications.
Who should not use it. The label says the product is not for anyone under 18.
How much does it cost, and what does a subscription commit you to?
As of October 28, 2026, the product page shows the prices below. Prices and bundles change, so check the checkout for today's price before you confirm.
| Option | Price as shown | Shipping and terms |
| One-time purchase | $21.99 | Pack size of 40 or 90 is chosen on the page. If the $21.99 is for the 40-count, that is about $0.55 per scoop. Confirm the count at checkout. |
| Subscribe & Save | $19.79 per shipment (10% off) | Delivery every 30, 45, 60 or 90 days, at the interval you select. The product page says free shipping applies. |
What a subscription commits you to. As shown on October 28, 2026, Subscribe & Save was $19.79 per shipment at the interval selected; the seller says the offer is subject to change. The seller's FAQ says you can change, pause or cancel before the next shipment date in your account portal or by contacting the company. The FAQ calls this a membership, with 10% off every order and free shipping. If you want a single order, choose the one-time purchase option at checkout instead.
Shipping. The promotional terms list general shipping thresholds, while the subscription FAQ says subscription orders get free shipping except that orders outside the contiguous U.S., including Alaska and Hawaii, are charged $8. Under the promotional terms, shipping is free for orders of $25 or more within the contiguous US, and an $8 charge applies to orders under $25.
First-order offer. The seller's promotional terms offer 25% off your first order when you sign up for emails. It is valid on one-time purchases, one per customer, and does not include tax or shipping. It excludes Subscribe & Save orders and Value Packs.
How do refunds, returns and cancelling work?
The seller sends questions about orders, shipping, returns and subscriptions to its help center. These are the steps:
- Open the help center before you order and find the return window and who pays return shipping.
- To cancel a subscription, change, pause or cancel it before the next shipment date in your account portal, or call 1-800-276-2878.
- Keep your order confirmation and note the lot and expiration dates printed on the package.
- If you need a return, get the window and steps from customer care in writing before you ship anything back.
Is Nature Made creatine legit, or is it a scam?
Yes, Nature Made is a real, long-running brand, and this creatine is sold on its own website. The About Us page says the company was founded in 1971. The site is run by a named company, and the label gives a phone number and a mailing address.
Here is what you can check yourself:
- Seller. The footer of the seller's site names Pharmavite LLC as the copyright holder. The label says the product is distributed by Nature Made Nutritional Products.
- Contact. Call 1-800-276-2878, or find the mailing address on the back of the package.
- Where it ships. The seller says it ships only to, and communicates only with, customers in the United States.
- Quality claims. The label says “Packaged and quality tested in the USA. Made to our guaranteed purity and potency standards.” The About Us page says the company works to make products USP verified when possible.
- NSF. The NSF Certified for Sport program describes itself as an independent third-party certification program recognized by USADA, Major League Baseball, the National Hockey League and the Canadian Football League, and says certified products are tested for 280+ banned substances. If you are tested under anti-doping rules, check the package you receive for that mark before you use it.
- FDA. The FDA's Questions and Answers on Dietary Supplements says that under DSHEA, the FDA does not have authority to approve dietary supplements before they are marketed. It says firms must follow current good manufacturing practices, and that a firm is responsible for making sure its supplements are not adulterated or misbranded.
- Adverse events. The FDA says supplement labels must give a domestic phone number or address for reporting serious adverse events. Anyone can report an adverse event to the FDA through its Safety Reporting Portal.
- Reviews. The product page shows a 4.5 rating from 124 reviews on the seller's own site. Read the written reviews, including the lower-rated ones, and compare them with the label.
How to protect yourself. Pay with a method that lets you dispute a charge with your bank if the order never arrives. Check the tamper-evident seal and expiration date when the package arrives. Keep your confirmation until the order is complete.
How does Nature Made creatine compare with other creatine options?
| Option | What the sources say |
| Nature Made creatine monohydrate powder | 5 g creatine monohydrate per scoop, unflavored; the seller directs one scoop daily. Antonio et al. 2021 says a loading phase is not required. Price and subscription terms are above. |
| Other creatine forms, such as HCl or ethyl ester | The seller says monohydrate is the most researched form. Antonio et al. 2021 says some forms may be more soluble in fluid, but creatine monohydrate is the optimal choice. |
| Food sources | The product page says creatine is found in red meat, seafood and animal milk, and that most people get it through their diet. |
| Exercise without creatine | Cleveland Clinic says creatine improves performance in short, high-intensity work without affecting aerobic endurance. The NIH says it has little value for endurance sports. |
If you are weighing a different brand, the Gym Floor Guide has a page on Thorne creatine, which covers ingredients, price and side effects. A separate comparison of thorne vs optimum nutrition creatine looks at price, safety and dose. For a creatine that comes as a chocolate bar, see the wonderfeel chococreatin review.
What to check before you order
- The pack size and the total at checkout, including shipping.
- Whether you have chosen one-time purchase or Subscribe & Save, and the delivery interval if you subscribe.
- The return window in the help center.
- The Servings Per Container line on the package you receive.
- Whether this lot carries USP verification or an NSF Certified for Sport mark.
- Your age, and your state's rules on delivery.
When you are ready, go to the Product Page and compare the one-time and subscription options side by side.
Short answers to other questions
Does Nature Made make creatine? Yes. This drink mix powder is Nature Made's creatine monohydrate product.
Does Nature Made make creatine gummies? The creatine on this page is a drink mix powder. The gummies on the seller's FAQ page are melatonin and elderberry gummies. The Gummies section of the seller's Products menu is the place to check for any other gummy.
Is Nature Made creatine monohydrate good? The seller says monohydrate is the most researched form, and Antonio et al. 2021 calls it the optimal choice. Whether it fits you depends on your training goals and your health, so bring your questions to a clinician.
Is Nature Made a good brand? The seller says it is the #1 Pharmacist Recommended Vitamin and Supplement Brand, based on a survey of pharmacists. That is the seller's claim.
Why am I always so tired even though I sleep a lot? Creatine is marketed for muscle function, not tiredness. Fatigue has many possible causes. MedlinePlus says fatigue is a symptom rather than a disease, and that if you have been tired for weeks, you should contact your health care provider. The MedlinePlus fatigue overview explains the difference between short-term tiredness and longer-lasting fatigue.
What are the warning signs of fatigue? The NHS self-help guide describes fatigue as overwhelming tiredness that rest and sleep do not relieve, and says it may point to an underlying medical condition. Talk to a doctor about tiredness that lasts.
What am I lacking if I'm always tired? MedlinePlus says fatigue is a symptom and a provider can help find the cause. Ask for a check rather than guessing at a deficiency.
What drink gets rid of fatigue? Healthline says being dehydrated leads to lower energy levels and decreased concentration. Healthline says energy drinks are extremely high in stimulants and added sugar and should be avoided whenever possible.
Next step: Pick the option that fits your month, check the total at checkout, and read the return window in the help center before you confirm.
Before you order: Ask the company whether this lot carries USP verification, and confirm the return window in writing.
By the Gym Floor Guide Editorial Team